The table below lists the pathways that have been deleted in RiceCyc version 1.3

Pathway
Reason for deletion
Biosynthesis - Amines and Polyamines
Choline-O-sulfate degradation
Microbial transformation of sulfur in the soil
Glycine betaine biosynthesis I (Gram-negative bacteria)
Gram-negative bacteria such as E. coli, Pseudomonas aeruginosa, and Synorhizobium meliloti utilize a choline dehydrogenase (EC 1.1.99.1)
Glycine betaine biosynthesis II (Gram-positive bacteria)
Gram-positive bacteria, such as Bacillus subtilis, use an alcohol dehydrogenase (EC 1.1.1.1)
Biosynthesis - Amino acids
Interconversion of arginine, ornithine and proline
Clostridium sticklandii, specific
Lysine biosynthesis V
prokaryote specific: the pathway continues in a path similar to bacterial arginine biosynthesis
Methionine biosynthesis III
bacteria, yeast and fungi can directly assimilate inorganic sulfur for the biosynthesis of sulfur-containing amino acids.
Biosynthesis - Cell structures
Enterobacterial common antigen biosynthesis
Enterobacteriaceae
Peptidoglycan biosynthesis
Peptidoglycan is found on the outside of the cytoplasmic membrane of almost all eubacteria, and is unique to these organisms.
UDP-N-acetyl-D-glucosamine biosynthesis
Pathway needs to be rebuilt
Biosynthesis - Cofactors, Prosthetic Groups, Electron Carriers
Cobalamin biosynthesis II (aerobic pathway)
The biosynthesis of coenzyme B12 is intricate and involved, and is confined to some bacteria and archaea
Mycothiol biosynthesis
Mycobacterium smegmatis
Biosynthesis - Fatty Acids and Lipids
Ergosterol biosynthesis
The ergosterol biosynthesis pathway is required for generation of a major constituent of the fungal plasma membrane
Biosynthesis - Hormones
Catecholamine biosynthesis
The catecholamines (norepinephrine, epinephrine and dopamine) are synthesized in the central nervous system (CNS), sympathetic nerves and in the chromaffin cells of the adrenal medulla.
Biosynthesis - Secondary Metabolites
Iisoflavonoid biosynthesis I
Isoflavonoids are restrictively distributed in the plant kingdom, being mostly biosynthesized in plants of the subfamily Papilionoideae of the Leguminosae.
Isoflavonoid biosynthesis II
Isoflavonoids are restrictively distributed in the plant kingdom, being mostly biosynthesized in plants of the subfamily Papilionoideae of the Leguminosae.
Biosynthesis - Siderophores
Enterobactin biosynthesis
Enterobacteriaceae
Biosynthesis - Sugars and Polysaccharides
Glycogen biosynthesis
Mammalian and yeast enzymes utilize UDP-D-glucose
Trehalose biosynthesis II
Saccharomyces cerevisiae - first EC number generalised
Degradation/Utilization/Assimilation - Amines and Polyamines
γ-butyrobetaine degradation
Pseudomonas species are able to grow on γ-butyrobetaine as their sole source of carbon and nitrogen.
Choline-O-sulfate degradation
Microbial transformation of sulfur in the soil
Superpathway of ornithine degradation
Bacteria
Degradation/Utilization/Assimilation - Amino Acids
Glutamate degradation VIII
Specific to Acidominococcaceae, Anaeromusa acidaminophila and Barkera propionica
Superpathway of arginine, putrescine, and 4-aminobutyrate degradation
Contains E.Coli specific sub pathways
Degradation/Utilization/Assimilation - C1 Compounds
Formaldehyde assimilation I (serine pathway)
Methanotrophic bacteria
Formaldehyde assimilation II (RuMP Cycle)
Methanotrophic bacteria
Formaldehyde oxidation I
Methanotrophic bacteria
Formaldehyde oxidation IV (thiol-independent)
Methanotrophic bacteria
Degradation/Utilization/Assimilation - Carboxylates
Methylcitrate cycle
Salmonella typhimurium and E.coli specific pathway
Degradation/Utilization/Assimilation - Other
Cyanide degradation
Chromobacterium violaceum specific pathway
D-camphor degradation
Camphor is a white, crystalline solid monoterpene ketone with a characteristic pungent odor and taste, which is naturally produced by the camphor tree
Octane oxidation
Pseudomonas putida PGo1 (formerly known as P. oleovorans) can utilize alkanes as a sole source of carbon and energy.
Thiocyanate degradation I
Microorganisms can use thiocyanate as a source of nitrogen, sulfur, carbon, or energy.
Degradation/Utilization/Assimilation - Sugars and Polysaccharides
Entner-Doudoroff pathway II (non-phosphorylative)
The classical Entner-Doudoroff (ED) pathway of bacteria (and some eukaryotes)
Entner-Doudoroff pathway III (semi-phosphorylative)
Found in halophilic archaea (and some bacteria), in which 2-keto-3-deoxygluconate (KDG) is phosphorylated to KDPG by KDG kinase, rather than the general conversion of glucose into glucose 6-phosphate
Glycogen degradation
Pathway specific for E.Coli
Lactose degradation II
Agrobacterium tumefaciens specific
Lactose degradation III
Escherichia coli, Sinorhizobium meliloti, Rhizobium meliloti specific pathway
Xylose degradation
D-xylose, which can serve as a total source of carbon and energy for E. coli
Generation of precursor metabolites and energy
Entner-Doudoroff pathway I
Escherichia coli specific pathway
Glucose fermentation to lactate II
This pathway is used by Bifidobacterium bifidum for glucose breakdown.
Glycolysis II
This glycolytic pathway in the archaeon Pyrococcus furiosus is a variant of the relatively well conserved glycolytic pathway in bacteria and eukaryotes
Purine fermentation to acetate and CO2
Clostridium specific pathway
TCA cycle variation II
Helicobacter pylori specific pathway
TCA cycle variation IV
Not supported by Metacyc
TCA cycle variation VIII
Not supported by Metacyc
Superpathways
Superpathway glycolysis+Entner Doudoroff
Subpathway no longer in RiceCyc
Superpathway glycolysis+TCA variation VIII
Subpathway no longer in RiceCyc

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