Pathway
|
Reason for deletion
|
Biosynthesis - Amines and Polyamines |
|
Choline-O-sulfate degradation |
Microbial transformation of sulfur in the soil |
Glycine betaine biosynthesis I (Gram-negative bacteria) |
Gram-negative bacteria such as E. coli, Pseudomonas aeruginosa, and Synorhizobium meliloti utilize a choline dehydrogenase (EC 1.1.99.1) |
Glycine betaine biosynthesis II (Gram-positive bacteria) |
Gram-positive bacteria, such as Bacillus subtilis, use an alcohol dehydrogenase (EC 1.1.1.1) |
Biosynthesis - Amino acids |
|
Interconversion of arginine, ornithine and proline |
Clostridium sticklandii, specific |
Lysine biosynthesis V |
prokaryote specific: the pathway continues in a path similar to bacterial arginine biosynthesis |
Methionine biosynthesis III |
bacteria, yeast and fungi can directly assimilate inorganic sulfur for the biosynthesis of sulfur-containing amino acids. |
Biosynthesis - Cell structures |
|
Enterobacterial common antigen biosynthesis |
Enterobacteriaceae |
Peptidoglycan biosynthesis |
Peptidoglycan is found on the outside of the cytoplasmic membrane of almost all eubacteria, and is unique to these organisms. |
UDP-N-acetyl-D-glucosamine biosynthesis |
Pathway needs to be rebuilt |
Biosynthesis - Cofactors, Prosthetic Groups, Electron Carriers |
|
Cobalamin biosynthesis II (aerobic pathway) |
The biosynthesis of coenzyme B12 is intricate and involved, and is confined to some bacteria and archaea |
Mycothiol biosynthesis |
Mycobacterium smegmatis |
Biosynthesis - Fatty Acids and Lipids |
|
Ergosterol biosynthesis |
The ergosterol biosynthesis pathway is required for generation of a major constituent of the fungal plasma membrane |
Biosynthesis - Hormones |
|
Catecholamine biosynthesis |
The catecholamines (norepinephrine, epinephrine and dopamine) are synthesized in the central nervous system (CNS), sympathetic nerves and in the chromaffin cells of the adrenal medulla. |
Biosynthesis - Secondary Metabolites |
|
Iisoflavonoid biosynthesis I |
Isoflavonoids are restrictively distributed in the plant kingdom, being mostly biosynthesized in plants of the subfamily Papilionoideae of the Leguminosae. |
Isoflavonoid biosynthesis II |
Isoflavonoids are restrictively distributed in the plant kingdom, being mostly biosynthesized in plants of the subfamily Papilionoideae of the Leguminosae. |
Biosynthesis - Siderophores |
|
Enterobactin biosynthesis |
Enterobacteriaceae |
Biosynthesis - Sugars and Polysaccharides |
|
Glycogen biosynthesis |
Mammalian and yeast enzymes utilize UDP-D-glucose |
Trehalose biosynthesis II |
Saccharomyces cerevisiae - first EC number generalised |
Degradation/Utilization/Assimilation - Amines and Polyamines |
|
γ-butyrobetaine degradation |
Pseudomonas species are able to grow on γ-butyrobetaine as their sole source of carbon and nitrogen. |
Choline-O-sulfate degradation |
Microbial transformation of sulfur in the soil |
Superpathway of ornithine degradation |
Bacteria |
Degradation/Utilization/Assimilation - Amino Acids |
|
Glutamate degradation VIII |
Specific to Acidominococcaceae, Anaeromusa acidaminophila and Barkera propionica |
Superpathway of arginine, putrescine, and 4-aminobutyrate degradation |
Contains E.Coli specific sub pathways |
Degradation/Utilization/Assimilation - C1 Compounds |
|
Formaldehyde assimilation I (serine pathway) |
Methanotrophic bacteria |
Formaldehyde assimilation II (RuMP Cycle) |
Methanotrophic bacteria |
Formaldehyde oxidation I |
Methanotrophic bacteria |
Formaldehyde oxidation IV (thiol-independent) |
Methanotrophic bacteria |
Degradation/Utilization/Assimilation - Carboxylates |
|
Methylcitrate cycle |
Salmonella typhimurium and E.coli specific pathway |
Degradation/Utilization/Assimilation - Other |
|
Cyanide degradation |
Chromobacterium violaceum specific pathway |
D-camphor degradation |
Camphor is a white, crystalline solid monoterpene ketone with a characteristic pungent odor and taste, which is naturally produced by the camphor tree |
Octane oxidation |
Pseudomonas putida PGo1 (formerly known as P. oleovorans) can utilize alkanes as a sole source of carbon and energy. |
Thiocyanate degradation I |
Microorganisms can use thiocyanate as a source of nitrogen, sulfur, carbon, or energy. |
Degradation/Utilization/Assimilation - Sugars and Polysaccharides |
|
Entner-Doudoroff pathway II (non-phosphorylative) |
The classical Entner-Doudoroff (ED) pathway of bacteria (and some eukaryotes) |
Entner-Doudoroff pathway III (semi-phosphorylative) |
Found in halophilic archaea (and some bacteria), in which 2-keto-3-deoxygluconate (KDG) is phosphorylated to KDPG by KDG kinase, rather than the general conversion of glucose into glucose 6-phosphate |
Glycogen degradation |
Pathway specific for E.Coli |
Lactose degradation II |
Agrobacterium tumefaciens specific |
Lactose degradation III |
Escherichia coli, Sinorhizobium meliloti, Rhizobium meliloti specific pathway |
Xylose degradation |
D-xylose, which can serve as a total source of carbon and energy for E. coli |
Generation of precursor metabolites and energy |
|
Entner-Doudoroff pathway I |
Escherichia coli specific pathway |
Glucose fermentation to lactate II |
This pathway is used by Bifidobacterium bifidum for glucose breakdown. |
Glycolysis II |
This glycolytic pathway in the archaeon Pyrococcus furiosus is a variant of the relatively well conserved glycolytic pathway in bacteria and eukaryotes |
Purine fermentation to acetate and CO2 |
Clostridium specific pathway |
TCA cycle variation II |
Helicobacter pylori specific pathway |
TCA cycle variation IV |
Not supported by Metacyc |
TCA cycle variation VIII |
Not supported by Metacyc |
Superpathways |
|
Superpathway glycolysis+Entner Doudoroff |
Subpathway no longer in RiceCyc |
Superpathway glycolysis+TCA variation VIII |
Subpathway no longer in RiceCyc |