[Objectives]
[Ontology Search] [Term Name] [Term ID]
[Synonyms] [Definition] [Lineage] [Term
Relationships] [Mutant/Protein Associations]
[Evidence codes]
[Ontology Flat Files] [Suggestions/Corrections]
Objectives:
Gramene (http://www.gramene.org)
is a comparative genome database for cereal crops and a community resource
for rice. We are populating and curating Gramene with annotated sequence
data and associated biological information including mutants, phenotypes,
polymorphisms and Quantitative Trait Loci. In order to support queries
across various data sets as well as across external databases, Gramene
is employing three related controlled vocabularies. First is the Trait
Ontology (TO) will be implemented across the cereal crops and plants
to curate and evaluate phenotype comparisons. An initial vocabulary for
TO and definitions for TO terms is available at http://www.gramene.org/plant_ontology/).
Second is a Plant Ontology (PO) will facilitate the curation of morphological
and anatomical feature information with respect to expression and localization
of gene and gene products. The TO and PO are both in the early stages of
development in collaboration with International Rice Research Institute,
TAIR, MaizeDB, International Crop Information System and CIMMYT. Finally,
as part of the Gene Ontology consortium,
we will classify confirmed or predicted rice gene products. The development
of plant specific vocabularies is open for community discussion.
Ontology database search:
The ontology search page
is divided into two sections. The first section allows you to query the
various terms and data sets contained in our ontology database. The
second is in interface that displays and allows navigation of the ontology
terms and their relations. Presently the data sets available for query
are Trait Ontology (TO)TM for rice and the Gene OntologyTM
terms mirrored from http://www.geneontology.org
Ontology Search Section:
In order to search for a
term type in term ID or keyword [e.g. cold tolerance or 303]
Ontology Display Section:
This is the major part of
QuickGO, and displays one GO term at a time, along with
various additional contextual
data including
Term Name:
This is the primary name
assigned to this term by either the GO consortium or the Gramene curator
for the rice TO. It is intended to be
sufficient to describe the
term without requiring any further reference to the structure of
the ontology.
Term ID:
This is the accession number
of this term. GO accessions are in the form 'GO:'
and TO accessions are in the form 'TO:'
followed by exactly seven decimal digits e.g. (GO:0006818),
(TO:0000303)
Synonyms (optional):
The synonyms are other alternate
names for this term. If there are no synonyms for the term you're viewing
then this box won't be present - the same applies to all the potentially
optional fields in the display.
for example
%cold tolerance ; TO:0000303 ; synonym:CTol
OR
%cytoplasmic male sterility type ; TO:0000232 ; synonym:MaizeDB-64827 ; synonym:CMS
Definition:
The optional definition,
if present, describes the term in more detail. GO / TO definitions are
drawn from a variety of
sources.
for example
term: 100-grain weight
goid: TO:0000269
definition: measurements in grams of 100 well-developed
whole grains, dried to 13% moisture content, weight on a precision balance.
Determine at growth stage 9
definition_reference: IRRI:SES
definition_reference: GR:pj37 (curator)
Lineage: Derivation
This box is always present,
and shows every possible path back from the selected term to the
root. Due to the 'strong path' property of the TO/GO, the implication is
that if a given trait term / gene product has been assigned an ID, it is
also implicitly mapped to all
the terms shown in this
display. Clicking on any of the terms in the lineage will select that term
as the current displayed term and refresh the window.
Term Relationships:
Parent and Child terms:
These boxes display the
immediate parents-children relationships of the currently selected term.
An example from a flat file:Parent-child relationships between terms are represented by indentation:parent_term
child_termInstance relationship: (marked by "%" percentage sign in the flat text files, or by [i] in the Ontology browser section)
%term0
%term1 % term2To be read as term1 being an instance of term0 and also an instance of term2. Part of relationship: (marked by "<" less than sign or by [p] in the Ontology browser section)
%term0
%term1 < term2 < term3
<fertility or sterility trait ; TO:0000392 < whole plant related trait ; TO:0000398
%fertility related trait ; TO:0000497
%female fertility restoration trait ; TO:0000498
%male fertility restoration trait ; TO:0000308 % hybrid evaluation ; TO:0000334
%incompatibility trait ; TO:0000035
%hybrid incompatibilty ; TO:0000036
%self-incompatibility trait ; TO:0000310
%sterility related trait ; TO:0000485
%female sterility trait ; TO:0000358
Note that terms may have
more than one parent, and may (obviously) have zero or more children. However,
currently there are no links between the TO and the three sub-ontologies
within GO. You can click on any of the terms in these lists to make the
clicked term the current one for display.
Mutant/Protein Associations:
Common Concurrent Assignments
This section, if present,
contains a list of TO/GO terms that are, statistically speaking,
commonly assigned to the mutants or proteins along with the currently displayed
term. For example, "hydrogen transport (GO:0006818)"
is mapped by various methods to approximately 19 proteins from rice
but four of such proteins from rice are also mapped to the "P-type ATPase
(GO:0015662)".
This display allows you to investigate potential conceptual linkages between
otherwise unrelated GO terms on the basis of their common assignment to
sets of proteins. This is just an example with the GO term, in future
we will provide the similar examples for the mutants and phenotypes associated
with the TO as well as GO terms.
Evidence codes:
Support each assertion of
phenotypic or the protein information from rice by evidence codes,
that describes the basis for the assertion of either the trait or the GO
components. The table of evidence codes is use by Gramene is available
at http://www.gramene.org/plant_ontology/evidence_codes.html
Links to Ontology flat files:
The flat files for the TO / GO terms and definitions can be downloaded from the following sites and can be browsed by using the stand-alone Browser
Trait OntologyTM for Rice: Trait terms Definitions Trait.zip File
Gene OntologyTM: Molecular function Biological process Cellular component Definitions
Suggestions/Corrections:
If you would like to make
any suggestion for the new term/definition/update/correction to an existing
term, please use the ONLINE
submission form the purpose. We appreciate your valuable feedback on
our efforts. Needless to mention your contribution will be duly acknowledged.
For more details on the Gene Ontology terms please refer to www.geneontology.org